ABSTRACT
In Spring 2020, Indigenous communities in northwest Saskatchewan, Canada, experienced the first significant outbreak of COVID-19. Through the collective efforts of public health measures by local, provincial, federal, and community partners, COVID-19 impacts were mitigated, and the severity of the outbreak in northwest Saskatchewan was limited. This article outlines the epidemiological profile of COVID-19 in the area during this period and the concomitant narrative of the public health control measures. The narrative connects specific culturally grounded approaches that were taken by community leaders and public health officials to moderate the pandemic's impacts and contain the outbreak. Among the lessons learned from these multi-jurisdictional efforts were the need to customize interventions to individual community characteristics and the benefits of continuous consultation and communication with community leadership. These findings suggest that long-term monetary investment in the strengths, assets, and capacity of communities can contribute toward sustainable solutions for existing structural inequities that have been amplified by the pandemic. The collaboration that resulted from local, provincial, and federal partnerships informed other pandemic response measures for subsequent outbreaks that have affected the region during the evolution of the COVID-19 pandemic.